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货号： bs-6734R-Bio 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-6734R-Bio
- 英文名称
- Anti-SERBP1/Biotin
- 中文名称
- 生物素标记的纤溶酶原激活物抑制剂1 RNA结合蛋白抗体
- 别 名
- CGI 55; CHD3IP; Chromodomain helicase DNA binding protein 3 interacting protein; HABP4L; PAI 1 mRNA binding protein; PAI RBP1; PAIRBP1; Plasminogen activator inhibitor 1 RNA binding protein; SERPINE1 mRNA binding protein 1; PAIRB_HUMAN.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 肿瘤 细胞生物 免疫学 信号转导 肿瘤细胞生物标志物 表观遗传学
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Chicken, Dog, Pig, Horse, Rabbit,
- 产品应用
- WB=1:50-200 ELISA=1:100-1000 IHC-P=1:50-200 IHC-F=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 45kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human SERBP1
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
SERBP1 (Plasminogen activator inhibitor 1 RNA-binding protein) may play a role in the regulation of mRNA stability. SERBP1 binds to the 3’-most 134 nt of the SERPINE1/PAI1 mRNA, a region which confers cyclic nucleotide regulation of message decay. SERBP1 interacts with CHD3 and is localized in cytoplasmic and nuclear. It is expressed at high level in the heart, skeletal muscle and kidney, and at low levels in placenta, liver and brain.
Function:
May play a role in the regulation of mRNA stability. Binds to the 3-most 134 nt of the SERPINE1/PAI1 mRNA, a region which confers cyclic nucleotide regulation of message decay.
Subunit:
Interacts with CHD3 and TDRD3.
Subcellular Location:
Cytoplasm. Nucleus. Cytoplasm, perinuclear region.
Tissue Specificity:
Expressed at high level in the heart, skeletal muscle and kidney, and at low levels in placenta, liver and brain.
Database links:Entrez Gene: 26135 Human
Entrez Gene: 66870 Mouse
Entrez Gene: 246303 Rat
Omim: 607378 Human
SwissProt: Q8NC51 Human
SwissProt: Q9CY58 Mouse
SwissProt: Q6AXS5 Rat
Unigene: 530412 Human
Unigene: 240490 Mouse
Unigene: 440861 Mouse
Unigene: 203108 Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.