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货号： bs-7061R-Bio 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-7061R-Bio
- 英文名称
- Anti-FAIM1/Biotin
- 中文名称
- 生物素标记的FAS凋亡抑制分子1抗体
- 别 名
- FAIM 1; FAIM; Fas apoptotic inhibitory molecule 1; Fas apoptotic inhibitory molecule; FAIM1_HUMAN.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 细胞生物 信号转导 细胞凋亡
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Sheep, Zebrafish
- 产品应用
- WB=1:50-200 ELISA=1:100-1000 IHC-P=1:50-200 IHC-F=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 20kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human FAIM1
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
FAIM1 (or Fas Apoptotic Inhibitory Molecule 1) is a recently discovered negative regulator of apoptosis. FAIM1 has no significant regions of homology to other gene products that modulate Fas killing. It plays a role as an inducible effector molecule that mediates Fas resistance produced by surface Ig engagement in B cells. Overexpression of FAIM1 diminishes sensitivity to Fas mediated apoptosis of B and non B cell lines. FAIM1 is highly evolutionarily conserved and is widely expressed in murine tissues, suggesting that FAIM1 plays an important role in cellular physiology.
Function:
Plays a role as an inducible effector molecule that mediates Fas resistance produced by surface Ig engagement in B cells (By similarity).
Subcellular Location:
Cytoplasm (By similarity).
Similarity:
Belongs to the FAIM1 family.
Database links:Entrez Gene: 55179 Human
Entrez Gene: 23873 Mouse
Entrez Gene: 100362113 Rat
Entrez Gene: 140930 Rat
SwissProt: Q9NVQ4 Human
SwissProt: Q9WUD8 Mouse
SwissProt: Q8R5H8 Rat
Unigene: 173438 Human
Unigene: 74605 Mouse
Unigene: 106419 Rat
Unigene: 199757 Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.