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货号： bs-7671R-Bio 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-7671R-Bio
- 英文名称
- Anti-NGFRAP1/Biotin
- 中文名称
- 生物素标记的神经生长因子受体相关蛋白1抗体
- 别 名
- NADE; BEX3; BEX3_HUMAN; Brain expressed X linked 3 (mouse) homolog; Brain-expressed X-linked protein 3; Nerve growth factor receptor (TNFRSF16) associated protein 1; Nerve growth factor receptor associated protein 1; Nerve growth factor receptor-associated protein 1; NGFRAP1; Ovarian granulosa cell 13.0 kDa protein HGR74; Ovarian granulosa cell protein; p75NTR associated cell death executor; p75NTR-associated cell death executor; Protein BEX3.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 细胞生物 神经生物学 细胞凋亡 细胞膜受体
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit,
- 产品应用
- WB=1:50-200 ELISA=1:100-1000 IHC-P=1:50-200 IHC-F=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 13kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human NADE/NGFRAP1
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
May be a signaling adapter molecule involved in p75NTR-mediated apoptosis induced by NGF. Plays a role in zinc-triggered neuronal death (By similarity). May play an important role in the pathogenesis of neurogenetic diseases.
Tissue specificity: Found in ovarian granulosa cells, testis, prostate and seminal vesicle tissue. High levels also detected in liver.
Function:
May be a signaling adapter molecule involved inp75NTR-mediated apoptosis induced by NGF. Plays a role inzinc-triggered neuronal death (By similarity). May play animportant role in the pathogenesis of neurogenetic diseases.
Subunit:
Self-associates. Interacts with 14-3-3 epsilon (YWHAE).Interacts with DIABLO/SMAC (By similarity). Binds to the DEATHdomain of p75NTR/NGFR.
Subcellular Location:
Nucleus. Cytoplasm. Note=Shuttles betweenthe cytoplasm and the nucleus. Associates with replicatingmitochondria (By similarity).
Tissue Specificity:
Found in ovarian granulosa cells, testis,prostate and seminal vesicle tissue. High levels also detected inliver.
Post-translational modifications:
Ubiquitinated. Degraded by the proteasome (By similarity).
Similarity:
Belongs to the BEX family.
Database links:Entrez Gene: 27018Human
Entrez Gene: 12070Mouse
Omim: 300361Human
SwissProt: Q00994Human
SwissProt: Q9WTZ9Mouse
Unigene: 448588Human
Unigene: 90787Mouse
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.