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货号： bs-7810R-Bio 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-7810R-Bio
- 英文名称
- Anti-MFAP1/Biotin
- 中文名称
- 生物素标记的微原纤维胶原相关蛋白1抗体
- 别 名
- MFAP1 is an extracellular protein associated with elastic fiber microfibrils.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 细胞生物 信号转导 细胞周期蛋白 细胞骨架 细胞外基质
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Chicken, Pig, Cow,
- 产品应用
- WB=1:50-200 ELISA=1:100-1000 IHC-P=1:50-200 IHC-F=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 52kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human MFAP1
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
Microfibrils are an important component of the extracellular matrix of many tissues and can either associate with or without elastin. Several microfibril associated proteins (MFAPs) have been cloned, including MFAP1, MFAP3 and MFAP4. The MFAP1 and MFAP3 genes are localized near the fibrillin genes FBN1 and FBN2, respectively. Mutations in FBN1 are linked to Marfan syndrome. Mutations in FBN2 have been linked to congenital contractural arachnodactyly. This suggests roles for MFAP1 and MFAP3 in heritable diseases affecting microfibrils. Deletion of MFAP4 was found in 30 of 31 patients with Smith-Magenis syndrome (SMS), a clinically recognizable multiple congenital anomaly/mental retardation syndrome.
Function:
Component of the elastin-associated microfibrils.
Subcellular Location:
Secreted, extracellular space, extracellular matrix.
Similarity:
Belongs to the MFAP1 family.
Database links:Entrez Gene: 510905Cow
Entrez Gene: 4236Human
Entrez Gene: 100034361Mouse
Entrez Gene: 67532Mouse
Omim: 600215Human
SwissProt: 5EA98Cow
SwissProt: P55081Human
SwissProt: Q9CQU1Mouse
Unigene: 61418Human
Unigene: 270393Mouse
Unigene: 440764Mouse
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.