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货号： bs-8239R-Bio 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-8239R-Bio
- 英文名称
- Anti-FRMD7/Biotin
- 中文名称
- 生物素标记的FRMD7蛋白抗体
- 别 名
- FERM domain-containing protein 7; FRMD7; FRMD7_HUMAN.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 细胞生物 免疫学 神经生物学
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Dog, Pig, Cow, Horse,
- 产品应用
- ELISA=1:100-1000 IHC-P=1:50-200 IHC-F=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 82kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human FRMD7
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
Mutations in this gene are associated with X-linked congenital nystagmus. [provided by RefSeq, Dec 2008]
Function:
Plays a role in neurite development (By similarity). May play a specific role in the control of eye movement and gaze stability.
Subcellular Location:
Cell projection. Cell projection, growth cone. Note=In undifferentiated neurons, located in the actin-rich regions of the cell body. In differentiated neurons, located in the actin-rich regions of the cell body and primary neurite processes but is almost absent from secondary extensions arising from the primary neurite. Also found at the actin-rich distal end of growth cones.
Tissue Specificity:
Expressed in liver, kidney, pancreas and at low levels in brain and heart. Expressed in embryonic brain and developing neural retina.
DISEASE:
Defects in FRMD7 are the cause of nystagmus congenital X-linked type 1 (NYS1) [MIM:310700]. NYS1 is a condition defined as conjugated, spontaneous and involuntary ocular oscillations that appear at birth or during the first three months of life. Other associated features may include mildly decreased visual acuity, strabismus, astigmatism, and occasionally head nodding.
Similarity:
Contains 1 FERM domain.
Database links:Entrez Gene: 90167Human
Omim: 300628Human
SwissProt: Q6ZUT3 Human
Unigene: 170776Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.