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货号： bs-20154R 基本售价： 1380.0 元 规格： 100ul
- 规格：100ul
- 价格：1380.00元
- 规格：200ul
- 价格：2200.00元
产品信息
- 产品编号
- bs-20154R
- 英文名称
- PCDH7
- 中文名称
- 原钙粘蛋白7抗体
- 别 名
- BH Pcdh; BH protocadherin; BH-Pcdh; BHPCDH; Brain heart protocadherin; Brain-heart protocadherin; PCDH 7; PCDH7; PCDH-7; PCDH7_HUMAN; Protocadherin 7; Protocadherin7; Protocadherin-7.
- 规格价格
- 100ul/1380元购买 200ul/2200元购买 大包装/询价
- 说 明 书
- 100ul 200ul
- 研究领域
- 神经生物学 信号转导 细胞粘附分子 细胞分化 细胞骨架 细胞膜蛋白
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Pig, Cow, Sheep,
- 产品应用
- WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 Flow-Cyt=2μg/Test ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 113kDa
- 细胞定位
- 细胞膜
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human PCDH7:31-130/1069
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- PubMed
- PubMed
- 产品介绍
- background:
As a subfamily of the cadherin superfamily, protocadherins are cadherin-like cell adhesion proteins that contain up to seven extracellular domains and are predominantly expressed in the nervous system. Importantly, the adhesion mechanism of protocadherins is distinct from classic cadherins. Through inactivation or overexpression, several protocadherins have been implicated in a variety of cancers. PCDH7 (protocadherin 7), also known as BHPCDH or BH-Pcdh, is a 1069 amino acid single-pass I membrane protein that is expressed in the brain and heart. Containing seven cadherin domains, PCDH7 is thought to function in cell-cell recognition and adhesion. PCDH7 exists as three isoforms due to alternative splicing events.
Function:
Expressed predominantly in brain and heart and at lower levels in various other tissues.
Subcellular Location:
Cell membrane.
Post-translational modifications:
Isoform C is phosphorylated upon DNA damage, probably by ATM or ATR.
Similarity:
Contains 7 cadherin domains.
SWISS:
O60245
Gene ID:
5099
Database links:Entrez Gene: 488843 Dog
Entrez Gene: 5099 Human
Entrez Gene: 54216 Mouse
Omim: 602988 Human
SwissProt: O60245 Human
Unigene: 479439 Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
- 产品图片
Sample: K562(human)cell Lysate at 40 ug
Primary: Anti-PCDH7 (bs-20154R) at 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 113 kD
Observed band size: 133 kD
Concebtration: 2ug/10^6 cells.
Positive control: Mouse brain cells.