产品中心
当前位置：首页>产品中心Anti-TRPM3/Biotin
货号： bs-9046R-Bio 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-9046R-Bio
- 英文名称
- Anti-TRPM3/Biotin
- 中文名称
- 生物素标记的瞬时受体电位离子通道蛋白3抗体（M亚家族）
- 别 名
- GON 2;GON2;Long transient receptor potential channel 3;LTRPC 3;LTRPC3;Melastatin 2;Melastatin2;MLSN 2;MLSN2;Transient receptor potential cation channel subfamily M member 3;transient receptor potential cation channel, subfamily M, member 3;TRPM 3;TRPM3 protein.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 肿瘤 细胞生物 免疫学 神经生物学 信号转导 通道蛋白
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep,
- 产品应用
- ELISA=1:100-1000 IHC-P=1:50-200 IHC-F=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 197kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human TRPM3
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
The product of this gene belongs to the family of transient receptor potential (TRP) channels. TRP channels are cation-selective channels important for cellular calcium signaling and homeostasis. The protein encoded by this gene mediates calcium entry, and this entry is potentiated by calcium store depletion. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008].
Function:
Calcium channel mediating constitutive calcium ion entry. Its activity is increased by reduction in extracellular osmolarity, by store depletion and muscarinic receptor activation.
Subcellular Location:
Membrane; Multi-pass membrane protein.
Tissue Specificity:
Expressed primarily in the kidney and, at lower levels, in brain, testis, ovary, pancreas and spinal cord. Expression in the brain and kidney was determined at protein level. In the kidney, expressed predominantly in the collecting tubular epithelium in the medulla, medullary rays, and periglomerular regions; in the brain, highest levels are found in the cerebellum, choroid plexus, the locus coeruleus, the posterior thalamus and the substantia nigra. Down-regulated in renal tumors compared to normal kidney.
Similarity:
Belongs to the transient receptor (TC 1.A.4) family. LTrpC subfamily. TRPM3 sub-subfamily.
Database links:Entrez Gene: 80036Human
Entrez Gene: 226025Mouse
Entrez Gene: 309407Rat
Omim: 608961Human
SwissProt: Q9HCF6Human
SwissProt: Q5F4S6Mouse
Unigene: 47288Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.