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货号： bs-9710R-Bio 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-9710R-Bio
- 英文名称
- Anti-NOP2/Biotin
- 中文名称
- 生物素标记的增殖相关核仁抗原抗体
- 别 名
- Proliferation Associated Nucleolar Antigen: NOL 1; NUCLEOLAR ANTIGEN p120; NOP2_HUMAN.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 肿瘤 细胞生物 信号转导 细胞凋亡 细胞周期蛋白 细胞分化 表观遗传学
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Dog, Cow, Horse, Rabbit, Sheep,
- 产品应用
- WB=1:50-200 ELISA=1:100-1000 IHC-P=1:50-200 IHC-F=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 89kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human NOL1
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
Proliferation-associated nucleolar antigen is expressed in mid G1 phase with peak level during the S phase and a rapid degradation during late mitosis. Its expression in breast carcinoma is correlated with patient prognosis.
Function:
May play a role in the regulation of the cell cycle andthe increased nucleolar activity that is associated with the cellproliferation. May act as ribosomal RNA methyltransferase.
Subunit:
Interaction with MCRS1.
Subcellular Location:
Nuclear
Similarity:
Belongs to the methyltransferase superfamily. RsmB/NOPfamily.
Database links:Entrez Gene: 4839 Human
Entrez Gene: 110109 Mouse
Entrez Gene: 314969 Rat
Omim: 164031 Human
SwissProt: P46087 Human
SwissProt: Q922K7 Mouse
Unigene: 534334 Human
Unigene: 29203 Mouse
Unigene: 32804 Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.