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货号： bs-9545R-Bio 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-9545R-Bio
- 英文名称
- Anti-C9orf86/Biotin
- 中文名称
- 生物素标记的9号染色体开放阅读框86抗体
- 别 名
- Chromosome 9 open reading frame 86; FLJ10101; Hypothetical protein LOC55684; KIAA1984; Parf; Partner of ARF; pp8875; Putative GTP binding protein Parf; Rab like GTP binding protein 1; Rab like GTP binding protein 1C; Rab like protein 1; RBEL1; RP11-216L13.9.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 肿瘤 细胞生物 表观遗传学
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat,
- 产品应用
- WB=1:50-200 ELISA=1:100-1000 IHC-P=1:50-200 IHC-F=1:50-200 ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 80kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human C9orf86
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
C9orf86 (Partner of ARF;PARF) binds p19(ARF), but not the p16(INK4A) isoform of CDKN2A. Knockdown of C9orf86 by RNA interference reduced the growth inhibitory activity of p19(ARF) and enhanced the rate of cell proliferation.
Function:
May enhance cellular proliferation. May reduce growth inhibitory activity of CDKN2A.
Subcellular Location:
Cytoplasmic and Nuclear. Note=Predominantly cytoplasmic. Proposed to shuttle between cytoplasm and nucleus.
Post-translational modifications:
Isoform 1 is O-glycosylated, while other isoforms are not.
Similarity:
Belongs to the small GTPase superfamily. Rab family.
Database links:Entrez Gene: 55684 Human
Entrez Gene: 227624 Mouse
Entrez Gene: 227624 Rat
Omim: 610615 Human
SwissProt: Q3YEC7 Human
SwissProt: Q5U3K5 Mouse
Unigene: 370555 Human
Unigene: 29600 Mouse
Unigene: 443064 Mouse
Unigene: 17709 Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.