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货号： bs-11177R-Bio 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-11177R-Bio
- 英文名称
- Anti-Trypsin Inhibitor/Biotin
- 中文名称
- 生物素标记的胰蛋白酶抑制剂抗体
- 别 名
- Peptidase inhibitor 15; PI-15; 25 kDa trypsin inhibitor; p25TI; Cysteine-rich secretory protein 8; CRISP-8; SugarCrisp; PI15_HUMAN.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 细胞生物 免疫学
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Sheep,
- 产品应用
- WB=1:50-200 ELISA=1:100-1000 IHC-P=1:50-200 IHC-F=1:50-200 ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 23kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human Trypsin Inhibitor
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
Cysteine-rich secretory proteins (CRISPs) represent a family of evolutionarily conserved proteins which play a role in the innate immune system and are transcriptionally regulated by androgens in several tissues. CRISP-8 (Cysteine-rich secretory protein 8), also known as PI15 (Peptidase inhibitor 15), P25TI or SugarCrisp, is a 258 amino acid secreted protein that belongs to the CRISP family. Expressed at low levels in thyroid, prostate, salivary and mammary tissue, CRISP-8 functions as a serine protease inhibitor that exhibits weak inhibitory action against Trypsin, a serine protease found in the digestive system. In addition to its role as a protease inhibitor, CRISP-8 is secreted in neuroblastoma and glioblastoma cell lines, suggesting a role for CRISP-8 in tumor formation and metastasis within the central nervous system.
Function:
The soybean trypsin inhibitor was first crystallized by Kunitz in 1945 and is Serine protease inhibitor which displays weak inhibitory activity against trypsin.
Subcellular Location:
Secreted.
Tissue Specificity:
Weakly expressed. Expressed at low level in prostate, mammary gland, salivary gland and thyroid gland.
Post-translational modifications:
N-glycosylated (Probable).
Similarity:
Belongs to the CRISP family.
Database links:
UniProtKB/Swiss-Prot: O43692.1
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.