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货号： bs-11212R-Bio 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-11212R-Bio
- 英文名称
- Anti-KLC1/Biotin
- 中文名称
- 生物素标记的驱动蛋白2抗体
- 别 名
- Kinesin 2 60/70kDa; Kinesin light chain 1; Kinesin2; Kinesin-2; KLC 1; KLC; KLC1; KLC1_HUMAN; KNS 2; KNS 2A; KNS2; KNS2A; Medulloblastoma antigen MU MB 2.50; MGC15245.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 神经生物学 信号转导 细胞骨架 细胞外基质
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Chicken, Cow, Horse, Rabbit, Zebrafish, Sheep,
- 产品应用
- WB=1:50-200 ELISA=1:100-1000 IHC-P=1:50-200 IHC-F=1:50-200 ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 65kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human KLC1
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
The kinesin family of motor proteins comprise at least two forms of conventional kinesin (kinesin-I). They are encoded by different genes and designated ubiquitous kinesin, which is expressed in all cells and tissues, and neuronal kinesin, which is expressed exclusively in neuronal cells. Conventional kinesin is a heterotetramer of two kinesin heavy chain subunits and two kinesin light chain subunits. While the kinesin heavy chain contains motor activity, evidence suggests that the kinesin light chain is involved in either modulation of kinesin heavy chain activity or in cargo binding. The motor protein kinesin is a heterotetramer composed of two heavy chains and two light chains. Kinesin motor activity is dependent on the presence of ATP and microtubules.
Function:
Kinesin is a microtubule-associated force-producing protein that may play a role in organelle transport. The light chain may function in coupling of cargo to the heavy chain or in the modulation of its ATPase activity.
Subunit:
Belongs to the kinesin light chain family.Contains 6 TPR repeats.
Subcellular Location:
Cytoplasm; cytoskeleton.
Tissue Specificity:
Found in a variety of tissues. Mostly abundant in brain and spine.
Post-translational modifications:
Isoform I is phosphorylated on Ser-600. Isoform J is phosphorylated on Ser-631.
Similarity:
Belongs to the kinesin light chain family.
Contains 6 TPR repeats.
Database links:Entrez Gene: 3831Human
Entrez Gene: 16593Mouse
Entrez Gene: 171041Rat
Omim: 600025Human
SwissProt: Q07866Human
SwissProt: O88447Mouse
SwissProt: P37285Rat
Unigene: 20107Human
Unigene: 657678Human
Unigene: 278357Mouse
Unigene: 106230Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.