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货号： bs-11552R-Bio 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-11552R-Bio
- 英文名称
- Anti-EN2/Biotin
- 中文名称
- 生物素标记的同源盒蛋白转录因子EN2抗体
- 别 名
- AUTS 1; AUTS1; EN 2; Engrailed 2; Engrailed homeo box 2; Engrailed homeobox 2; Engrailed homolog 2; Engrailed2; Homeobox protein engrailed 2; Homeobox protein engrailed2; Hu En 2; HuEn2; MabEn; HME2_HUMAN; Homeobox protein engrailed-2; Homeobox protein en-2; Hu-En-2.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 细胞生物 神经生物学 信号转导 干细胞 表观遗传学
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Dog, Pig, Sheep,
- 产品应用
- WB=1:50-200 ELISA=1:100-1000 IHC-P=1:50-200 IHC-F=1:50-200 ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 34kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human EN2/Engrailed 2 (281-333aa)
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
Homeobox-containing genes are thought to have a role in controlling development. In Drosophila, the engrailed (en) gene plays an important role during development in segmentation, where it is required for the formation of posterior compartments. Different mutations in the mouse homologs, En1 and En2, produced different developmental defects that frequently are lethal. The human engrailed homologs 1 and 2 encode homeodomain-containing proteins and have been implicated in the control of pattern formation during development of the central nervous system. [provided by RefSeq, Jul 2008].
Function:
EN1 and EN2 encode homeodomain containing proteins and have been implicated in the control of pattern formation during development of the central nervous system. EN2 may play a role in susceptibility to autism spectrum disorders.
Subcellular Location:
Nuclear.
DISEASE:
Note=Genetic variations in EN2 may be associated with susceptibility to autism.
Similarity:
Belongs to the engrailed homeobox family.
Contains 1 homeobox DNA-binding domain.
Database links:Entrez Gene: 2020Human
Entrez Gene: 13799Mouse
Entrez Gene: EN2Rat
Omim: 131310Human
SwissProt: Q05917Chicken
SwissProt: P19622Human
SwissProt: P09066Mouse
Unigene: 134989Human
Unigene: 4298Mouse
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.