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货号： bs-11639R-Bio 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-11639R-Bio
- 英文名称
- Anti-APPBP2/Biotin
- 中文名称
- 生物素标记的β淀粉样蛋白前体蛋白结合蛋白2抗体
- 别 名
- amyloid beta precursor protein (cytoplasmic tail) binding protein 2; Amyloid beta precursor protein-binding protein 2; Amyloid protein binding protein 2; Amyloid protein-binding protein 2; APBP2_HUMAN; APP BP2; APP-BP2; Appbp2; PAT1; Ara67 Protein interacting with APP tail 1.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 免疫学 神经生物学 Alzheimers
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Dog, Pig, Cow, Zebrafish,
- 产品应用
- WB=1:50-200 ELISA=1:100-1000 IHC-P=1:50-200 IHC-F=1:50-200 ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 67kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human APPBP2
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
The protein encoded by this gene interacts with microtubules and is functionally associated with beta-amyloid precursor protein transport and/or processing. The beta-amyloid precursor protein is a cell surface protein with signal-transducing properties, and it is thought to play a role in the pathogenesis of Alzheimers disease. This gene has been found to be highly expressed in breast cancer. Multiple polyadenylation sites have been found for this gene. [provided by RefSeq, Jul 2008].
Function:
May play a role in intracellular protein transport. May be involved in the translocation of APP along microtubules toward the cell surface.
Subunit:
Binds APP.
Subcellular Location:
Nucleus. Cytoplasm
Post-translational modifications:
Rapidly degraded by the proteasome upon overexpression of a C-terminal fragment of APP.
Similarity:
Contains 8 TPR repeats.
Database links:Entrez Gene: 10513 Human
Entrez Gene: 66884 Mouse
Entrez Gene: 303396 Rat
Entrez Gene: 417645 Chicken
Omim: 605324 Human
SwissProt: Q92624 Human
SwissProt: Q9DAX9 Mouse
SwissProt: A5HK05 Rat
Unigene: 84084 Human
Unigene: 271997 Mouse
Unigene: 104856 Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.