产品中心
当前位置：首页>产品中心Anti-LIN9
货号： bs-18283R 基本售价： 1380.0 元 规格： 100ul
- 规格：100ul
- 价格：1380.00元
- 规格：200ul
- 价格：2200.00元
产品信息
- 产品编号
- bs-18283R
- 英文名称
- LIN9
- 中文名称
- LIN9蛋白抗体
- 别 名
- BARA; Beta subunit-associated regulator of apoptosis; Beta-subunit associated regulator of apoptosis; hLin-9; huLin-9; lin-9; lin9; LIN9_HUMAN; pRB-associated protein; Protein lin-9 homolog; TGS; TUDOR gene similar protein; Type I interferon receptor beta chain-associated protein.
- 规格价格
- 100ul/1380元购买 200ul/2200元购买 大包装/询价
- 说 明 书
- 100ul 200ul
- 研究领域
- 细胞生物 细胞凋亡 细胞周期蛋白 表观遗传学
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Cynomolgus Monkey
- 产品应用
- WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 62kDa
- 细胞定位
- 细胞核
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human LIN9:
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- PubMed
- PubMed
- 产品介绍
- background:
This gene encodes a tumor suppressor protein that inhibits DNA synthesis and oncogenic transformation through association with the retinoblastoma 1 protein. The encoded protein also interacts with a complex of other cell cycle regulators to repress cell cycle-dependent gene expression in non-dividing cells. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jul 2012]
Function:
Acts as a tumor suppressor. Inhibits DNA synthesis. Its ability to inhibit oncogenic transformation is mediated through its association with RB1. Plays a role in the expression of genes required for the G1/S transition.
Subcellular Location:
Nucleus > nucleoplasm. Found in perinucleolar structures. Associated with chromatin.
Tissue Specificity:
Expressed in thymus and testis.
Similarity:
Belongs to the lin-9 family.
SWISS:
Q5TKA1
Gene ID:
286826
Database links:Entrez Gene: 286826Human
Entrez Gene: 421316Chicken
Entrez Gene: 72568Mouse
Entrez Gene: 689523Rat
Entrez Gene: 323027Zebrafish
Entrez Gene: 560867Zebrafish
Omim: 609375Human
SwissProt: Q5TKA1Human
SwissProt: Q8C735Mouse
SwissProt: Q5RHQ8Zebrafish
Unigene: 120817Human
Unigene: 275044Mouse
Unigene: 214693Rat
Unigene: 76676Zebrafish
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
- 产品图片
Sample:
Bone (Mouse) Lysate at 40 ug
Primary: Anti-LIN9 (bs-18283R) at 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 62 kD
Observed band size: 62 kD
Tissue/cell: human kidney tissue; 4% Paraformaldehyde-fixed and paraffin-embedded;
Antigen retrieval: citrate buffer ( 0.01M, pH 6.0 ), Boiling bathing for 15min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30min; Blocking buffer (normal goat serum,C-0005) at 37℃ for 20 min;
Incubation: Anti-LIN9 Polyclonal Antibody, Unconjugated(bs-18283R) 1:200, overnight at 4°C, followed by conjugation to the secondary antibody(SP-0023) and DAB(C-0010) staining