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货号： bs-11798R-Bio 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-11798R-Bio
- 英文名称
- Anti-Reticulon 1/Biotin
- 中文名称
- 生物素标记的神经内分泌特异性蛋白抗体
- 别 名
- MGC133250; Neuroendocrine specific protein; NSP; Reticulon 1; Reticulon1; Reticulon1A; RTN 1; RTN1; RTN1 protein; RTN1_HUMAN.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 肿瘤 细胞生物 神经生物学 肿瘤细胞生物标志物
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Pig,
- 产品应用
- WB=1:50-200 ELISA=1:100-1000 IHC-P=1:50-200 IHC-F=1:50-200 ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 84kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human Reticulon 1
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
This gene belongs to the family of reticulon encoding genes. Reticulons are associated with the endoplasmic reticulum, and are involved in neuroendocrine secretion or in membrane trafficking in neuroendocrine cells. This gene is considered to be a specific marker for neurological diseases and cancer, and is a potential molecular target for therapy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2011]
Function:
May be involved in neuroendocrine secretion or in membrane trafficking in neuroendocrine cells.
Subunit:
Interacts with NDRG1.
Subcellular Location:
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Tissue Specificity:
Expressed in neural and neuroendocrine tissues and cell cultures derived therefrom. Expression of isoform RTN1-C is strongly correlated with neuronal differentiation.
Post-translational modifications:
Isoforms RTN1-A and RTN1-B are phosphorylated.
Similarity:
Contains 1 reticulon domain.
Database links:Entrez Gene: 6252Human
Entrez Gene: 116644Rat
Omim: 600865Human
SwissProt: Q16799Human
SwissProt: Q64548Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.