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货号： bs-11801R-Bio 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-11801R-Bio
- 英文名称
- Anti-SLC14A2/Biotin
- 中文名称
- 生物素标记的尿素转运型糖蛋白A2抗体
- 别 名
- UT-A; HUT2; kidney; MGC119566; MGC119567; Slc14a2; Solute carrier family 14 (urea transporter), member 2; Solute carrier family 14 member 2; Urea transporter 2; Urea transporter; Urea transporter, kidney; UT-A2; UT2; UT2_HUMAN; UTA; UTR; FLJ16167; hUT-A6.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 肿瘤 神经生物学 信号转导 通道蛋白 新陈代谢
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat,
- 产品应用
- WB=1:50-200 ELISA=1:100-1000 IHC-P=1:50-200 IHC-F=1:50-200 ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 101kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human SLC14A2/UT-A
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
The protein encoded by this gene belongs to the urea transporter family. In mammalian cells, urea is the chief end product of nitrogen catabolism, and plays an important role in the urinary concentration mechanism. This protein is expressed in the inner medulla of the kidney, and mediates rapid transepithelial urea transport across the inner medullary collecting duct. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Sep 2011]
Function:
Specialized low-affinity vasopressin-regulated urea transporter. Mediates rapid transepithelial urea transport across the inner medullary collecting duct and plays a major role in the urinary concentrating mechanism.
Subunit:
Isoform 1 interacts with SNAPIN which may be important for recruitment to the plasma membrane.
Subcellular Location:
Apical cell membrane; Multi-pass membrane protein.
Tissue Specificity:
Isoform 1 and isoform 2 are expressed in the inner medulla of the kidney.
Similarity:
Belongs to the urea transporter family.
Database links:Entrez Gene: 8170Human
Entrez Gene: 27411Mouse
Entrez Gene: 54302Rat
Omim: 601611Human
SwissProt: Q15849Human
SwissProt: Q8R4T9Mouse
SwissProt: Q62668Rat
Unigene: 710927Human
Unigene: 44158Mouse
Unigene: 10157Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.