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货号： bs-17798R-AF594 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-17798R-AF594
- 英文名称
- Anti-RASL11A/AF594
- 中文名称
- AF594标记的Ras样蛋白家族11A抗体
- 别 名
- Ras-like protein family member 11A; RAS-like, family 11, member A; Rasl11a; RSLBA_HUMAN.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- 产品应用
- ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 37kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 2mg/1ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human RASL11A
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
RASL11A is a member of the small GTPase protein family with a high degree of similarity to RAS (see HRAS, MIM 190020) proteins.[supplied by OMIM, Nov 2008]
Function:
Regulator of rDNA transcription. Acts in cooperation UBF/UBTF and positively regulates RNA polymerase I transcription.
Subunit:
Interacts with UBF/UBTF.
Subcellular Location:
Nucleus, nucleolus. Associates with rDNA transcription unit throughout the cell cycle.
Tissue Specificity:
Widely expressed. Down-regulated in prostate tumors compared to normal prostate tissue. High levels found in colon tumor and normal colon tissue followed by small intestine, liver, jejunum, ileum, bladder and aorta. Lowest levels observed in endothelial cells.
Similarity:
Belongs to the small GTPase superfamily. Ras family.
Database links:Entrez Gene: 387496 Human
Entrez Gene: 68895 Mouse
Entrez Gene: 304268 Rat
Omim: 612403 Human
SwissProt: Q6T310 Human
SwissProt: Q6IMB1 Mouse
SwissProt: Q6IMA3 Rat
Unigene: 192131 Human
Unigene: 266978 Mouse
Unigene: 105901 Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.