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货号： bs-4381R-AF594 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-4381R-AF594
- 英文名称
- Anti-ZNF769/RB associated KRAB repressor/AF594
- 中文名称
- AF594标记的锌指蛋白769抗体
- 别 名
- RB associated KRAB repressor;hRBaK; Hypothetical protein RBAK; RB associated KRAB zinc finger; RB-associated KRAB repressor; RB-associated KRAB zinc finger protein; RBAK; RBAK_HUMAN; Zinc finger protein 769; ZNF 769; ZNF769.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 转录调节因子 锌指蛋白 表观遗传学
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- 产品应用
- ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 83kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 2mg/1ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human ZNF769
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
This gene encodes a nuclear protein which interacts with the tumor suppressor retinoblastoma 1. The two interacting proteins are thought to act as a transcriptional repressor for promoters which are activated by the E2F1 transcription factor. This protein contains a Kruppel-associated box (KRAB), which is a transcriptional repressor motif. Read-through transcripts that include exons from the downstream gene LOC389458 are expressed from this locus. [provided by RefSeq, Mar 2011]
Function:
May repress E2F-dependent transcription. May promote AR-dependent transcription.
Subcellular Location:
Nucleus.
Tissue Specificity:
Expressed in bone, brain, heart, kidney, liver, lung, pancreas and placenta.
Similarity:
Belongs to the krueppel C2H2-type zinc-finger protein family.
Contains 16 C2H2-type zinc fingers.
Contains 1 KRAB domain.
Database links:Entrez Gene: 57786Human
Entrez Gene: 57782Mouse
Omim: 608191Mouse
SwissProt: Q9NYW8Human
SwissProt: Q8BQC8Mouse
Unigene: 396178Human
Unigene: 320419Mouse
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.