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货号： bs-4404R-AF594 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-4404R-AF594
- 英文名称
- Anti-NUP188/AF594
- 中文名称
- AF594标记的核孔蛋白188抗体
- 别 名
- BC025526; FLJ21639; hNup188; KIAA0169; mKIAA0169; Nucleoporin 188kDa; Nucleoporin NUP188 homolog; OTTMUSP00000018197; RP11-167N5.2; RP23-395P6.3; U89435.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 细胞生物 染色质和核信号
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Sheep,
- 产品应用
- ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 196kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 2mg/1ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human NUP188
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
The nuclear pore complex (NPC) is found on the nuclear envelope and forms a gateway that regulates the flow of proteins and RNAs between the cytoplasm and nucleoplasm. The NPC is comprised of approximately 30 distinct proteins collectively known as nucleoporins. Nucleoporins are pore-complex-specific glycoproteins which often have cytoplasmically oriented O-linked N-acetylglucosamine residues and numerous repeats of the pentapeptide sequence XFXFG. However, the nucleoporin protein encoded by this gene does not contain the typical FG repeat sequences found in most vertebrate nucleoporins. This nucleoporin is thought to form part of the scaffold for the central channel of the nuclear pore. [provided by RefSeq, Jan 2013]
Function:
May function as a component of the nuclear pore complex (NPC).
Subcellular Location:
Nucleus, nuclear pore complex.
DISEASE:
Copy number variations of NUP188 gene may be a cause of heterotaxy, a congenital heart disease resulting from abnormalities in left-right (LR) body patterning.
Database links:Entrez Gene: 23511Human
Entrez Gene: 227699Mouse
Entrez Gene: 366016Rat
Omim: 615587Human
SwissProt: Q5SRE5Human
SwissProt: Q6ZQH8Mouse
Unigene: 308340Human
Unigene: 330119Mouse
Unigene: 11918Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.