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货号： bs-4431R-AF594 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-4431R-AF594
- 英文名称
- Anti-PTPN20/AF594
- 中文名称
- AF594标记的蛋白酪氨酸磷酸酶非受体型20抗体
- 别 名
- bA42B19.1; hPTPN20; Protein tyrosine phosphatase non receptor type 20; PTN20_HUMAN; PTP Typ; PTP Typ; Ptpn20; PTPN20A; PTPN20B; Tyrosine-protein phosphatase non-receptor type 20.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 细胞生物 信号转导 激酶和磷酸酶
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Pig,
- 产品应用
- ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 48kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 2mg/1ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human PTPN20
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
The product of this gene belongs to the family of classical tyrosine-specific protein tyrosine phosphatases. Many protein tyrosine phosphatases have been shown to regulate fundamental cellular processes. The encoded protein appears to be targeted to sites of actin polymerization. A pseudogene of this gene has been defined on chromosome 10. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2014]
Function:
Tyrosine-protein phosphatase targeted to sites of actin polymerization in response of varied extracellular stimuli. Has tyrosine phosphatase activity towards various tyrosyl phosphorylated substrates.
Subcellular Location:
Nucleus. Cytoplasm. Cytoplasm > cytoskeleton > centrosome. Colocalizes with the microtubule-organizing center and intracellular membrane compartments.
Tissue Specificity:
Present in many cell lines (at protein level). Widely expressed.
Post-translational modifications:
Phosphorylated upon DNA damage, probably by ATM or ATR.
Similarity:
Belongs to the protein-tyrosine phosphatase family.
Non-receptor class subfamily.
Contains 1 tyrosine-protein phosphatase domain.
Database links:Entrez Gene: 26095Human
Entrez Gene: 653129Human
Omim: 610630Human
Omim: 610631Human
SwissProt: Q4JDL3Human
Unigene: 440733Human
Unigene: 499552Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.