产品中心
当前位置：首页>产品中心Anti-SEC61B/AF594
货号： bs-4455R-AF594 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-4455R-AF594
- 英文名称
- Anti-SEC61B/AF594
- 中文名称
- AF594标记的转运蛋白SEC61B抗体
- 别 名
- Protein translocation complex beta; Protein transport protein SEC61 beta subunit; Protein transport protein Sec61 subunit beta; SC61B_HUMAN; SEC 61B; SEC61; SEC61 B; Sec61 beta subunit; Sec61 complex beta subunit; SEC61B.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 细胞生物 信号转导 转运蛋白
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Sheep,
- 产品应用
- ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 10kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 2mg/1ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human SEC61B
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
The Sec61 complex is the central component of the protein translocation apparatus of the endoplasmic reticulum (ER) membrane. Oligomers of the Sec61 complex form a transmembrane channel where proteins are translocated across and integrated into the ER membrane. This complex consists of three membrane proteins- alpha, beta, and gamma. This gene encodes the beta-subunit protein. The Sec61 subunits are also observed in the post-ER compartment, suggesting that these proteins can escape the ER and recycle back. There is evidence for multiple polyadenylated sites for this transcript. [provided by RefSeq, Jul 2008]
Function:
Necessary for protein translocation in the endoplasmic reticulum.
Subcellular Location:
Endoplasmic reticulum membrane.
Similarity:
Belongs to the SEC61-beta family.
Database links:Entrez Gene: 10952Human
Entrez Gene: 66212Mouse
Entrez Gene: 298068Rat
Omim: 609214Human
SwissProt: P60467Dog
SwissProt: P60468Human
SwissProt: Q9CQS8Mouse
Unigene: 191887Human
Unigene: 20188Mouse
Unigene: 103030Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.