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货号： bs-21102R-AF594 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-21102R-AF594
- 英文名称
- Anti-SEZ6L2/AF594
- 中文名称
- AF594标记的癫痫相关蛋白6样蛋白2抗体
- 别 名
- FLJ90517; PSK 1; PSK; SE6L2_HUMAN; Seizure 6 like protein 2; Seizure 6-like protein 2; Seizure related 6 homolog (mouse) like 2; SEZ6L2; Type I transmembrane receptor (seizure related protein).
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 神经生物学 信号转导
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Dog, Pig, Cow, Rabbit, Sheep,
- 产品应用
- ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 98kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 2mg/1ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human SEZ6L2
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
This gene encodes a seizure-related protein that is localized on the cell surface. The gene is located in a region of chromosome 16p11.2 that is thought to contain candidate genes for autism spectrum disorders (ASD), though there is no evidence directly implicating this gene in ASD. Increased expression of this gene has been found in lung cancers, and the protein is therefore considered to be a novel prognostic marker for lung cancer. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Aug 2011]
Function:
Protein-lysine N-methyltransferase that specifically monomethylates Lys-310 of the RELA subunit of NF-kappa-B complex, leading to down-regulate NF-kappa-B transcription factor activity.
Subcellular Location:
Cell membrane. Endoplasmic reticulum membrane. Detected on cell surface of lung-cancer.
Post-translational modifications:
O-glycosylated with core 1 or possibly core 8 glycans.
Similarity:
Belongs to the SEZ6 family.
Contains 3 CUB domains.
Contains 5 Sushi (CCP/SCR) domains.
Database links:Entrez Gene: 26470Human
SwissProt: Q29RN8Cow
SwissProt: Q6UXD5Human
SwissProt: Q6AX42 Xenopus laevis
Unigene: 6314Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.