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货号： bs-21153R-AF594 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-21153R-AF594
- 英文名称
- Anti-RANBP17/AF594
- 中文名称
- AF594标记的RAN结合蛋白17抗体
- 别 名
- Exp 7; Exp7; Exportin 7; Exportin7; KIAA0745; RAN binding protein 16; RANBP 16; XPO 7; XPO7.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 细胞生物 信号转导 结合蛋白 G蛋白信号
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Pig, Cow, Horse, Rabbit, Sheep, Guinea Pig, Chimpanzee,
- 产品应用
- ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 124kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 2mg/1ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human RANBP17
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
The transport of protein and large RNAs through the nuclear pore complexes (NPC) is an energy-dependent and regulated process. The import of proteins with a nuclear localization signal (NLS) is accomplished by recognition of one or more clusters of basic amino acids by the importin-alpha/beta complex; see MIM 600685 and MIM 602738. The small GTPase RAN (MIM 601179) plays a key role in NLS-dependent protein import. RAN-binding protein-17 is a member of the importin-beta superfamily of nuclear transport receptors.[supplied by OMIM, Jul 2002]
Function:
May function as a nuclear transport receptor.
Subcellular Location:
Cytoplasm. Nucleus. Nucleus > nuclear pore complex.
Tissue Specificity:
Highly expressed in testis, moderately in pancreas and weakly in other tissues studied.
Similarity:
Belongs to the exportin family.
Database links:Entrez Gene: 739299Chimpanzee
Entrez Gene: 529222Cow
Entrez Gene: 479293Dog
Entrez Gene: 64901Human
Entrez Gene: 100526145Pig
Entrez Gene: 303029Rat
Omim: 606141Human
SwissProt: Q9H2T7Human
Unigene: 410810Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.