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货号： bs-20098R-AF594 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-20098R-AF594
- 英文名称
- Anti-PRPF4/AF594
- 中文名称
- AF594标记的PRPF4蛋白抗体
- 别 名
- HPRP4; HPRP4P; PRP4; PRP4 pre mRNA processing factor 4 homolog (yeast); PRP4/STK/WD splicing factor; Prp4p; U4/U6 small nuclear ribonucleoprotein Prp4; WD splicing factor Prp4; PRP4_HUMAN.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 细胞生物 细胞周期蛋白 细胞分化 表观遗传学
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Dog, Pig, Cow, Rabbit, Sheep,
- 产品应用
- ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 58kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 2mg/1ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human PRPF4
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
Pre-mRNA splicing occurs in two sequential transesterification steps, and the protein encoded by this gene is thought to be involved in pre-mRNA splicing and in signal transduction. This protein belongs to a kinase family that includes serine/arginine-rich protein-specific kinases and cyclin-dependent kinases (CDKs). This protein is regarded as a CDK-like kinase (Clk) with homology to mitogen-activated protein kinases (MAPKs). [provided by RefSeq, Jul 2008]
Function:
Involved in pre-mRNA splicing.
Subunit:
Interacts directly with PRPF18, PPIH and PRPF3. Part of a heteromeric complex containing PPIH, PRPF3 and PRPF4 that is stable in the absence of RNA. This complex interacts with the U4/U5/U6 tri-snRNP complex.
Subcellular Location:
Nucleus speckle. Note=Colocalizes with spliceosomal snRNPs.
Similarity:
Contains 7 WD repeats.
Database links:Entrez Gene: 8899 Human
Entrez Gene: 19134 Mouse
Entrez Gene: 291078 Rat
Omim: 602338 Human
SwissProt: Q08DZ2 Cow
SwissProt: Q13523 Human
SwissProt: Q61136 Mouse
SwissProt: Q5RKH1 Rat
Unigene: 159014 Human
Unigene: 10027 Mouse
Unigene: 482253 Mouse
Unigene: 32654 Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.