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货号: bs-21253R-AF594 基本售价: 2980.0 元 规格: 100ul
产品信息
- 产品编号
- bs-21253R-AF594
- 英文名称
- Anti-SLC30A4/AF594
- 中文名称
- AF594标记的溶质载体转运蛋白家族30成员4抗体
- 别 名
- Dri 27 protein; Lethal milk protein; Slc30a4; Solute carrier family 30 (zinc transporter), member 4; Solute carrier family 30 member 4; Zinc transporter 4; ZnT-4; Znt4; ZNT4_HUMAN.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 细胞生物 神经生物学 信号转导 转运蛋白
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Cow,
- 产品应用
- ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 47kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 2mg/1ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human SLC30A4
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
Zinc is the second most abundant trace metal in the human body. It is an essential element, serving both a structural role, as in the formation of zinc fingers in DNA-binding proteins, and a catalytic role in metalloenzymes, such as pancreatic carboxypeptidases (e.g., MIM 114852), alkaline phosphatases (e.g., MIM 171760), various dehydrogenases, and superoxide dismutases (e.g., MIM 147450). SLC30A4, or ZNT4, belongs to the ZNT family of zinc transporters. ZNTs are involved in transporting zinc out of the cytoplasm and have similar structures, consisting of 6 transmembrane domains and a histidine-rich cytoplasmic loop (Huang and Gitschier, 1997 [PubMed 9354792]).[supplied by OMIM, Mar 2008]
Function:
Probably involved in zinc transport out of the cytoplasm, maybe by sequestration into an intracellular compartment.
Subcellular Location:
Endosome membrane.
Similarity:
Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family.
SLC30A subfamily.
Database links:Entrez Gene: 7782Human
Omim: 602095Human
SwissProt: O14863Human
Unigene: 162989Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.