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货号： bs-20255R-AF594 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-20255R-AF594
- 英文名称
- Anti-MAP1A/AF594
- 中文名称
- AF594标记的微管相关蛋白1A抗体
- 别 名
- MAP 1A; MAP-1A; MTAP1A; MAP 1L; MAP1L; MAP1A heavy chain; Map1a; MAP1A_HUMAN; Microtubule associated protein 1 like; Microtubule Associated Protein 1A; Microtubule-associated protein 1A; MTAP1A; Proliferation related protein p80; Proliferation-related protein p80; AI853608; Map1a; moth1; Mtap-1; Mtap1.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 肿瘤 细胞生物 免疫学 神经生物学 信号转导 细胞凋亡
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Cow, Horse, Sheep,
- 产品应用
- ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 326kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 2mg/1ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human MAP1A
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
This gene encodes a protein that belongs to the microtubule-associated protein family. The proteins of this family are thought to be involved in microtubule assembly, which is an essential step in neurogenesis. The product of this gene is a precursor polypeptide that presumably undergoes proteolytic processing to generate the final MAP1A heavy chain and LC2 light chain. Expression of this gene is almost exclusively in the brain. Studies of the rat microtubule-associated protein 1A gene suggested a role in early events of spinal cord development. [provided by RefSeq, Jul 2008]
Function:
Structural protein involved in the filamentous cross-bridging between microtubules and other skeletal elements.
Subunit:
3 different light chains, LC1, LC2 and LC3, can associate with MAP1A and MAP1B proteins. Interacts with TIAM2. Interacts with guanylate kinase-like domain of DLG1, DLG2, DLG4. Binds to CSNK1D.
Subcellular Location:
Cytoplasm, cytoskeleton (Probable).
Tissue Specificity:
Brain
Post-translational modifications:
Phosphorylated by CSNK1D.
LC2 is generated from MAP1A by proteolytic processing.
Similarity:
Belongs to the MAP1 family.
Database links:Entrez Gene: 4130 Human
Entrez Gene: 17754 Mouse
Entrez Gene: 25152 Rat
Omim: 600178 Human
SwissProt: P78559 Human
SwissProt: Q9QYR6 Mouse
SwissProt: P34926 Rat
Unigene: 194301 Human
Unigene: 619338 Human
Unigene: 36501 Mouse
Unigene: 11402 Rat
Unigene: 41412 Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.