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货号: bs-20452R-AF594 基本售价: 2980.0 元 规格: 100ul
产品信息
- 产品编号
- bs-20452R-AF594
- 英文名称
- Anti-DLX2/AF594
- 中文名称
- AF594标记的同源转录因子DLX2抗体
- 别 名
- DII A; Distal less homeo box 2; Distal less homeobox 2; Distal-less homeobox 2; DLX 2; Dlx2; DLX2_HUMAN; Dlx5; Homeobox protein DLX 2; Homeobox protein DLX-2; Homeobox protein DLX2; Homeobox protein TES 1; Homeobox protein TES-1; Homeobox protein TES1; Tes 1; Tes-1; Tes1; zgc.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 细胞生物 神经生物学 信号转导 干细胞 表观遗传学
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat,
- 产品应用
- ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 34kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 2mg/1ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human DLX2
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
Dlx genes are a highly conserved family of six different (Dlx1–6) homeo box-containing genes that share homology with distal-less (Dll), a gene expressed in the head and limbs of the developing fruit fly. Dlx genes are expressed in spatially and temporally restricted patterns in craniofacial primordia, basal telencephalon and diencephalon, and in distal regions of extending appendages, including the limb and the genital bud. The differential expression of Dlx influences patterning, morphogenesis and histogenesis in these tissues. The Dlx gene products can activate transcription and are localized primarily to the nucleus, although Dlx-5 can be found in the cytoplasm. Dlx proteins influence different stages of proper tissue development, including patterning of the orofacial skeleton (craniofacial ectomesenchyme) and differentiation of structures within and between teeth.
Function:
Likely to play a regulatory role in the development of the ventral forebrain. May play a role in craniofacial patterning and morphogenesis.
Subcellular Location:
Nucleus.
Similarity:
Belongs to the distal-less homeobox family.
Contains 1 homeobox DNA-binding domain.
Database links:Entrez Gene: 1746 Human
Entrez Gene: 13392 Mouse
Omim: 126255 Human
SwissProt: Q07687 Human
SwissProt: P40764 Mouse
Unigene: 419 Human
Unigene: 3896 Mouse
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.