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货号： bs-20420R-AF594 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-20420R-AF594
- 英文名称
- Anti-NR2F1 + NR2F2/AF594
- 中文名称
- AF594标记的载脂蛋白AI调节蛋白1抗体
- 别 名
- Apolipoprotein AI regulatory protein 1; ARP1; COUP TF1; COUP TF2; COUP transcription factor 2; Chicken ovalbumin upstream promoter 1; COT1_HUMAN; COUP transcription factor 1; COUP transcription factor I; COUP-TF I; COUP-TF1; EAR-3; EAR3; ERBAL3; NR2F1; NR2F2; Nuclear receptor subfamily 2 group F member 1; SVP44; TCFCOUP1; TFCOUP1; Transcription factor COUP 1; V ERBA related protein EAR 3; V-erbA-related protein 3.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 肿瘤 心血管 细胞生物 免疫学 染色质和核信号 神经生物学 信号转导 生长因子和激素 细胞分化 表观遗传学
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- 产品应用
- ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 46kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 2mg/1ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human NR2F1 + NR2F2
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
NR2F2 is involved in the regulation of the apolipoprotein A-I gene transcription. It binds to DNA site A as a homodimer. It belongs to the nuclear hormone receptor family, NR2 subfamily. It has roles in angiogenesis, vascular remodeling and heart development.
Function:
Coup (chicken ovalbumin upstream promoter) transcription factor binds to the ovalbumin promoter and, in conjunction with another protein (S300-II) stimulates initiation of transcription. Binds to both direct repeats and palindromes of the 5-AGGTCA-3 motif. Represses transcriptional activity of LHCG.
Subunit:
Binds DNA as dimer; homodimer and probable heterodimer with NR2F6. Interacts with COPS2.
Subcellular Location:
Nucleus (Probable).
Similarity:
Belongs to the nuclear hormone receptor family. NR2 subfamily.
Contains 1 nuclear receptor DNA-binding domain
Database links:Entrez Gene: 281945 Cow
Entrez Gene: 7026 Human
Entrez Gene: 11819 Mouse
Entrez Gene: 113984 Rat
Omim: 107773 Human
SwissProt: Q9TTR7 Cow
SwissProt: P24468 Human
SwissProt: P43135 Mouse
SwissProt: O09018 Rat
Unigene: 347991 Human
Unigene: 17815 Rat
Entrez Gene: 7025 Human
Entrez Gene: 13865 Mouse
Entrez Gene: 81808 Rat
Omim: 132890 Human
SwissProt: P10589 Human
SwissProt: Q60632 Mouse
Unigene: 519445 Human
Unigene: 439653 Mouse
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.