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货号： bs-8745R-AF555 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-8745R-AF555
- 英文名称
- Anti-XRCC2/AF555
- 中文名称
- AF555标记的X射线修复交叉互补蛋白2抗体
- 别 名
- DKFZp781P0919; DNA repair protein XRCC2; X ray repair complementing defective repair in Chinese hamster cells 2; X ray repair cross complementing protein 2; X-ray repair cross-complementing protein 2; Xrcc2; XRCC2_HUMAN.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 细胞生物 表观遗传学
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Dog, Pig, Horse, Rabbit,
- 产品应用
- ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 32kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 2mg/1ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human XRCC2
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
Involved in the homologous recombination repair (HRR) pathway of double-stranded DNA, thought to repair chromosomal fragmentation, translocations and deletions. The BCDX2 complex binds single-stranded DNA, single-stranded gaps in duplex DNA and specifically to nicks in duplex DNA.
Function:
Involved in the homologous recombination repair (HRR) pathway of double-stranded DNA, thought to repair chromosomal fragmentation, translocations and deletions. The BCDX2 complex binds single-stranded DNA, single-stranded gaps in duplex DNA and specifically to nicks in duplex DNA.
Subcellular Location:
Nucleus.
Post-translational modifications:
Phosphorylated upon DNA damage, probably by ATM or ATR.
Similarity:
Belongs to the RecA family. RAD51 subfamily.
Database links:Entrez Gene: 7516Human
Entrez Gene: 57434Mouse
Entrez Gene: 499966Rat
Omim: 600375Human
SwissProt: O43543Human
SwissProt: Q9CX47Mouse
Unigene: 647093Human
Unigene: 143767Mouse
Unigene: 8224Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.