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货号： bs-8741R-AF555 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-8741R-AF555
- 英文名称
- Anti-SNRPN/AF555
- 中文名称
- AF555标记的小核糖核蛋白N抗体
- 别 名
- HCERN3; PWCR; RSMN_HUMAN; RT LI; RTLI; SM D; Sm N; Sm protein D; Sm protein N; Sm-D; Sm-N; Small nuclear ribonucleoprotein associated protein N; Small nuclear ribonucleoprotein polypeptide N; Small nuclear ribonucleoprotein-associated protein N; SMD; SmN; SNRNP N; snRNP-N; SNRNPN; SNRPN; SNURF SNRPN; Tissue specific splicing protein; Tissue-specific-splicing protein.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 细胞生物 转录调节因子 表观遗传学
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Pig, Cow, Horse, Rabbit, Sheep,
- 产品应用
- ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 25kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 2mg/1ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human SNRPN
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
This gene is located within the Prader-Willi Syndrome critical region on chromosome 15 and is imprinted and expressed from the paternal allele. It encodes a component of the small nuclear ribonucleoprotein complex, which functions in pre-mRNA processing and may contribute to tissue-specific alternative splicing. Alternative promoter use and alternative splicing result in a multitude of transcript variants encoding the same protein. Transcript variants that initiate at the CpG island-associated imprinting center may be bicistronic and also encode the SNRPN upstream reading frame protein (SNURF) from an upstream open reading frame. In addition, long spliced transcripts for small nucleolar RNA host gene 14 (SNHG14) may originate from the promoters at this locus and share exons with this gene. Alterations in this region are associated with parental imprint switch failure, which may cause Angelman syndrome or Prader-Willi syndrome. [provided by RefSeq, Mar 2017]
Function:
May be involved in tissue-specific alternative RNA processing events.
Subcellular Location:
Nucleus.
Tissue Specificity:
Expressed in brain and lymphoblasts.
Similarity:
Belongs to the snRNP SmB/SmN family.
Database links:Entrez Gene: 780877Cow
Entrez Gene: 6638Human
Entrez Gene: 20646Mouse
Entrez Gene: 84704Mouse
Entrez Gene: 81781Rat
Omim: 182279Human
SwissProt: Q17QN3Cow
SwissProt: Q60HD3 Cynomolgus Monkey
SwissProt: P63162Human
SwissProt: P63163Mouse
SwissProt: Q5R6I0Orangutan
SwissProt: P63164Rat
Unigene: 555970Human
Unigene: 564847Human
Unigene: 578619Human
Unigene: 585703Human
Unigene: 592473Human
Unigene: 621316Human
Unigene: 632166Human
Unigene: 728856Human
Unigene: 274995Mouse
Unigene: 11169Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.