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货号： bs-21143R-AF555 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-21143R-AF555
- 英文名称
- Anti-Adipolin/AF555
- 中文名称
- AF555标记的Adipolin蛋白抗体
- 别 名
- RAI150; FAM132A; C1QDC2; CTRP12; Family With Sequence Similarity 132, Member A; C1q And TNF Related Protein 12; C1q/TNF-Related Protein 12; Protein FAM132A; hypothetical protein LOC67389; RIKEN cDNA 1110035L05; C1q And TNF Related 12; C1q And Tumor Necrosis Factor Related Protein 12; Adipose-Derived Insulin-Sensitizing Factor; Complement C1q Tumor Necrosis Factor-Related Protein 12; Family With Sequence Similarity 132 Member A; C1q Domain Containing 2; ADIPL_HUMAN;
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 细胞生物 免疫学 糖尿病
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Dog, Pig, Horse,
- 产品应用
- ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 33kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 2mg/1ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human Adipolin
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
C1QTNF12 (C1q And TNF Related 12) is a Protein Coding gene. An important paralog of this gene is ERFE.
Function:
Insulin-sensitizing adipocyte-secreted protein (adipokine) that regulates glucose metabolism in liver and adipose tissue. Promotes glucose uptake in adipocytes and suppresses de novo glucose production in hepatocytes via the PI3K-Akt signaling pathway. Administration lead to reduction of blood glucose. Able to attenuate inflammation in fat tissue.
Subunit:
Homomultimer; disulfide-linked. May interact with ERFE (By similarity).
Subcellular Location:
Extracellular region or secreted
Tissue Specificity:
Predominantly expressed by adipose tissues.
Post-translational modifications:
Processed into Adipolin fC1QTNF12 and Adipolin gC1QTNF12 by FURIN. Insulin enhances endogenous C1QTNF12 cleavage.
Similarity:
Belongs to the adipolin/erythroferrone family.
Database links:Entrez Gene: 388581 Human
SwissProt: Q5T7M4 Human
Unigene: 197613 Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.