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货号： bs-8010R-AF555 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-8010R-AF555
- 英文名称
- Anti-WNT 5B/AF555
- 中文名称
- AF555标记的信号通路Wnt-5a抗体
- 别 名
- MGC2648; Wnt5b;Protein Wnt-5b; Wingless type MMTV integration site family, member 5B; WNT 5B; WNT 5B protein; Wnt5b; WNT5B protein; WNT5B_HUMAN.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 细胞生物 信号转导 干细胞
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat,
- 产品应用
- ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 38kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 2mg/1ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human WNT 5B
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It encodes a protein which shows 94% and 80% amino acid identity to the mouse Wnt5b protein and the human WNT5A protein, respectively. Alternative splicing of this gene generates 2 transcript variants. [provided by RefSeq, Jul 2008]
Function:
Ligand for members of the frizzled family of seven transmembrane receptors. Probable developmental protein. May be a signaling molecule which affects the development of discrete regions of tissues. Is likely to signal over only few cell diameters.
Subunit:
Interacts with PORCN.
Subcellular Location:
Secreted > extracellular space > extracellular matrix.
Similarity:
Belongs to the Wnt family.
Database links:Entrez Gene: 508008Cow
Entrez Gene: 486756Dog
Entrez Gene: 81029Human
Entrez Gene: 22419Mouse
Entrez Gene: 100349579Rabbit
Entrez Gene: 282582Rat
Entrez Gene: 30105Zebrafish
Omim: 606361Human
SwissProt: Q9H1J7Human
SwissProt: P22726Mouse
SwissProt: Q92050Zebrafish
Unigene: 306051Human
Unigene: 321818Mouse
Unigene: 58724Rat
Unigene: 389Zebrafish
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.