产品中心
当前位置：首页>产品中心Anti-CYT 19
货号： bs-10633R 基本售价： 1380.0 元 规格： 100ul
- 规格：100ul
- 价格：1380.00元
- 规格：200ul
- 价格：2200.00元
产品信息
- 产品编号
- bs-10633R
- 英文名称
- CYT 19
- 中文名称
- 甲基转移酶cyt-19抗体
- 别 名
- 2310045H08Rik; CYT19; Arsenic (+3 oxidation state) methyltransferase; Arsenite methyltransferase; As3mt; AS3MT_HUMAN; C10ORF32; CYT19; Cyt19 protein; Hypothetical protein C10orf32; Methylarsonite methyltransferase; Methyltransferase cyt19; OTTHUMP00000020384; RP11-753C18.6; S adenosylmethionine arsenic (III) methyltransferase; S-adenosyl-L-methionine:arsenic(III) methyltransferase.
- 规格价格
- 100ul/1380元购买 200ul/2200元购买 大包装/询价
- 说 明 书
- 100ul 200ul
- 研究领域
- 肿瘤 细胞生物 信号转导 新陈代谢
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Chicken, Dog, Cow, Horse, Rabbit, Sheep,
- 产品应用
- WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 42kDa
- 细胞定位
- 细胞核
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human CYT 19:21-120/375
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- PubMed
- PubMed
- 产品介绍
- background:
Formation of methylated metabolites is a critical step in the metabolism of inorganic arsenic. Arsenite methyltransferase (cyt19) is localized to the cytoplasm and operates in the transfer of a methyl group from AdoMet to trivalent arsenicals producing methylated and dimethylated arsenicals. It methylates arsenite to form methylarsonate which is reduced to methylarsonite. Methylarsonite acts as a substrate and is converted into a much less toxic compound dimethylarsinate. cyt19 is highly expressed in liver. Inherited variation in cyt19 may contribute to variation in arsenic metabolism and possibly arsenic-dependent carcinogenesis in humans.
Function:
Catalyzes the transfer of a methyl group from AdoMet to trivalent arsenicals producing methylated and dimethylated arsenicals. It methylates arsenite to form methylarsonate, Me-AsO(3)H(2), which is reduced by methylarsonate reductase to methylarsonite, Me-As(OH)2. Methylarsonite is also a substrate and it is converted into the much less toxic compound dimethylarsinate (cacodylate), Me(2)As(O)-OH.
Subcellular Location:
Cytoplasm.
Similarity:
Belongs to the methyltransferase superfamily.
SWISS:
Q9HBK9
Gene ID:
57412
Database links:Entrez Gene: 57412 Human
Entrez Gene: 57344 Mouse
Entrez Gene: 140925 Rat
Omim: 611806 Human
SwissProt: Q9HBK9 Human
SwissProt: Q91WU5 Mouse
SwissProt: Q8VHT6 Rat
Unigene: 720370 Human
Unigene: 28566 Mouse
Unigene: 95453 Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
- 产品图片
Protein: heart(mouse) lysate at 40ug;
Primary: rabbit Anti-CYT 19 (bs-10633R) at 1:300;
Secondary: HRP conjugated Goat-Anti-rabbit IgG(bs-0295G-HRP) at 1: 5000;
Predicted band size: 42 kD
Observed band size: 42 kD
Sample:
heart (Mouse) Lysate at 40 ug
liver (Mouse) Lysate at 40 ug
Primary: Anti-CYT 19 (bs-10633R) at 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 42 kD
Observed band size: 48 kD