产品中心
当前位置：首页>产品中心Anti-RAD51AP1/AF555
货号： bs-19725R-AF555 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-19725R-AF555
- 英文名称
- Anti-RAD51AP1/AF555
- 中文名称
- AF555标记的RAD51相互作用蛋白1抗体
- 别 名
- 2510006L10Rik; MGC156698; OTTMUSP00000028651; PIR51; R51A1_HUMAN; RAB22; RAD51 associated protein 1; RAD51 interacting protein; RAD51-associated protein 1; RAD51-interacting protein; Rad51ap1.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 细胞生物 转录调节因子 表观遗传学
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat,
- 产品应用
- ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 38kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human RAD51AP1
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- Function:
May participate in a common DNA damage response pathway associated with the activation of homologous recombination and double-strand break repair. Functionally cooperates with PALB2 in promoting of D-loop formation by RAD51. Binds to single and double stranded DNA, and is capable of aggregating DNA. Also binds RNA.
Subcellular Location:
Nucleus. Colocalizes with RAD51 to multiple nuclear foci.
Tissue Specificity:
Highly expressed in testis and thymus. Lower levels in colon and small intestine. Little or no expression in spleen, prostate, ovary and peripheral blood leukocytes.
Post-translational modifications:
Phosphorylated upon DNA damage, probably by ATM or ATR.
Similarity:
Belongs to the methyltransferase superfamily. METTL21 family.
Database links:Entrez Gene: 10635Human
Omim: 603070Human
SwissProt: Q96B01Human
Unigene: 504550Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.