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货号： bs-18973R-AF555 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-18973R-AF555
- 英文名称
- Anti-Myosin IXA/AF555
- 中文名称
- AF555标记的肌球蛋白9A抗体
- 别 名
- 4732465J09Rik; C130068I12Rik; C230003M11; FLJ11061; FLJ13244; MGC71859; Myo9a; MYO9A variant protein; MYO9A_HUMAN; Myosin-IXa; MYR7; Unconventional myosin 9a; Unconventional myosin-9a.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 细胞生物 信号转导
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Horse, Sheep, Recombinant Fragment, Recombinant Fragment, Macaque Monkey
- 产品应用
- ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 293kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human Myosin IXA
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
This gene encodes a member of the myosin superfamily. The protein represents an unconventional myosin; it should not be confused with the conventional non-muscle myosin-9 (MYH9). Unconventional myosins contain the basic domains of conventional myosins and are further distinguished from class members by their tail domains. They function as actin-based molecular motors. Mutations in this gene have been associated with Bardet-Biedl Syndrome. [provided by RefSeq, Dec 2011]
Function:
Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. Regulates Rho activity in neurons, has a role in the regulation of neuronal morphology and function.
Subcellular Location:
Membrane.
Tissue Specificity:
Found to be expressed in testis and placenta, and at lower levels in all the examined tissues with the exception of liver. Isoform 5 was found in leukocytes but not in brain, retina or testis.
Similarity:
Contains 5 IQ domains.
Contains 2 myosin head-like domains.
Contains 2 phorbol-ester/DAG-type zinc fingers.
Contains 1 Ras-associating domain.
Contains 1 Rho-GAP domain.
Database links:Entrez Gene: 4649Human
Entrez Gene: 270163Mouse
Entrez Gene: 171296Rat
Omim: 604875Human
SwissProt: B2RTY4Human
SwissProt: Q8C170Mouse
SwissProt: Q9Z1N3Rat
Unigene: 546268Human
Unigene: 249545Mouse
Unigene: 88901Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.