产品中心
当前位置：首页>产品中心Anti-MONDOA/AF555
货号： bs-18957R-AF555 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-18957R-AF555
- 英文名称
- Anti-MONDOA/AF555
- 中文名称
- AF555标记的MONDOA蛋白抗体
- 别 名
- MLX-interacting protein;BHLHE36; Class E basic helix loop helix protein 36; MIR; MLXIP; MONDOA; Transcriptional activator MondoA.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 细胞生物 转录调节因子 表观遗传学
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Cow, Rabbit, Sheep,
- 产品应用
- ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 101kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human MONDOA
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
This gene encodes a protein that functions as part of a heterodimer to activate transcription. The encoded protein forms a heterodimer with Max-like protein X (MLX) and is involved in the regulation of genes in response to cellular glucose levels. [provided by RefSeq, Mar 2014]
Function:
Binds DNA as a heterodimer with MLX and activates transcription. Binds to the canonical E box sequence 5-CACGTG-3. Plays a role in transcriptional activation of glycolytic target genes. Involved in glucose-responsive gene regulation.
Subunit:
Efficient DNA binding requires dimerization with another bHLH protein. Binds DNA as a homodimer or a heterodimer with MLX.
Subcellular Location:
Cytoplasm. Nucleus. Mitochondrion outer membrane.
Tissue Specificity:
Widely expressed in adult tissues. Most abundant in skeletal muscle. Ref.1
Similarity:
Contains 1 bHLH (basic helix-loop-helix) domain.
Database links:Entrez Gene: 22877Human
Entrez Gene: 208104Mouse
Omim: 608090Human
SwissProt: Q9HAP2Human
SwissProt: Q2VPU4Mouse
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.