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货号： bs-18896R-AF555 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-18896R-AF555
- 英文名称
- Anti-MFI2/MAP97/AF555
- 中文名称
- AF555标记的黑色素瘤相关抗原P97抗体
- 别 名
- Antigen p97; CD228; CD228 antigen; MAP97; Melanoma associated antigen p97; Melanoma-associated antigen p97; Melanotransferrin; Mfi2; MTF1; TRFM_HUMAN.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 肿瘤 细胞生物 信号转导 转录调节因子 表观遗传学
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Dog, Pig, Cow, Rabbit, Sheep,
- 产品应用
- ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 76, 90kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human MFI2/MAP97
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
The protein encoded by this gene is a cell-surface glycoprotein found on melanoma cells. The protein shares sequence similarity and iron-binding properties with members of the transferrin superfamily. The importance of the iron binding function has not yet been identified. This gene resides in the same region of chromosome 3 as members of the transferrin superfamily. Alternative splicing results in two transcript variants. [provided by RefSeq, Jul 2008]
Function:
Involved in iron cellular uptake. Seems to be internalized and then recycled back to the cell membrane. Binds a single atom of iron per subunit. Could also bind zinc.
Subcellular Location:
Cell membrane.
Tissue Specificity:
Found predominantly in human melanomas and in certain fetal tissues; also found in liver, epithelium, umbilical chord, placenta and sweat gland ducts.
Similarity:
Belongs to the transferrin family.
Contains 2 transferrin-like domains.
Database links:Entrez Gene: 4241Human
Omim: 155750Human
SwissProt: P08582Human
Unigene: 184727Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.