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货号： bs-18787R-AF555 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-18787R-AF555
- 英文名称
- Anti-MEMO1/AF555
- 中文名称
- AF555标记的MEMO1蛋白抗体
- 别 名
- C21orf19-like protein; C2orf4; CGI 27; DKFZp434I0135; FLJ25031; HCV NS5A-transactivated protein 7; Hepatitis C virus NS5A-transactivated protein 7; Mediator of cell motility 1; Mediator of ErbB2-driven cell motility 1; MEMO; Memo-1; memo1; MEMO1_HUMAN; NS5ATP7; Protein MEMO1.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 肿瘤 细胞生物 信号转导 激酶和磷酸酶 结合蛋白 细胞骨架
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Dog, Cow, Horse,
- 产品应用
- ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 34kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human MEMO1
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- Function:
May control cell migration by relaying extracellular chemotactic signals to the microtubule cytoskeleton. Mediator of ERBB2 signaling. The MEMO1-RHOA-DIAPH1 signaling pathway plays an important role in ERBB2-dependent stabilization of microtubules at the cell cortex. It controls the localization of APC and CLASP2 to the cell membrane, via the regulation of GSK3B activity. In turn, membrane-bound APC allows the localization of the MACF1 to the cell membrane, which is required for microtubule capture and stabilization. Is required for breast carcinoma cell migration.
Subunit:
Interacts with ERBB2 phosphorylated on Tyr-1248.
Similarity:
Belongs to the UPF0103 family.
Database links:Entrez Gene: 51072Human
Entrez Gene: 615803Cow
Entrez Gene: 76890Mouse
Entrez Gene: 298787Rat
Entrez Gene: 327360Zebrafish
Omim: 611786Human
SwissProt: Q2HJH7Cow
SwissProt: Q9Y316Human
SwissProt: Q91VH6Mouse
SwissProt: Q4QQR9Rat
SwissProt: Q803S3Zebrafish
Unigene: 43892Cow
Unigene: 444969Human
Unigene: 311874Mouse
Unigene: 22312Rat
Unigene: 14259Zebrafish
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.