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货号： bs-18771R-AF555 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-18771R-AF555
- 英文名称
- Anti-MED4/AF555
- 中文名称
- AF555标记的MED4蛋白抗体
- 别 名
- Activator-recruited cofactor 36 kDa component; ARC36; DRIP36; FLJ10956; HSPC126; med4; MED4_HUMAN; Mediator complex subunit 4; Mediator of RNA polymerase II transcription subunit 4; Mediator of RNA polymerase II transcription, subunit 4 homolog; OTTHUMP00000018390; OTTHUMP00000018391; OTTHUMP00000018392; RP11-90M2.2; TRAP/SMCC/PC2 subunit p36 subunit; TRAP36; VDRIP; Vitamin D3 receptor-interacting protein complex 36 kDa component.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 转录调节因子 表观遗传学
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Sheep,
- 产品应用
- ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 30kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human MED4
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
This gene encodes a component of the Mediator complex. The Mediator complex interacts with DNA-binding gene-specific transcription factors to modulate transcription by RNA polymerase II. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jul 2012]
Function:
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
Subcellular Location:
Nucleus.
Similarity:
Belongs to the Mediator complex subunit 4 family.
Database links:Entrez Gene: 29079Human
Entrez Gene: 418859Chicken
Entrez Gene: 515299Cow
Entrez Gene: 67381Mouse
Entrez Gene: 306030Rat
Entrez Gene: 550582Zebrafish
Omim: 605718Human
SwissProt: Q3SYZ9Cow
SwissProt: Q9NPJ6Human
SwissProt: Q3UL96Mouse
SwissProt: Q8BVG6Mouse
SwissProt: Q9CQA5Mouse
SwissProt: Q561Q8Rat
SwissProt: Q561X3Zebrafish
Unigene: 181112Human
Unigene: 282888Mouse
Unigene: 114469Rat
Unigene: 84720Zebrafish
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.