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货号: bs-18706R-AF555 基本售价: 2980.0 元 规格: 100ul
产品信息
- 产品编号
- bs-18706R-AF555
- 英文名称
- Anti-MBLAC2/AF555
- 中文名称
- AF555标记的MBLAC2蛋白抗体
- 别 名
- DKFZp686P15118; MBLAC2; MBLC2_HUMAN; Metallo beta lactamase domain containing protein 2; Metallo-beta-lactamase domain-containing protein 2; MGC46734.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 肿瘤 细胞生物 信号转导
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse,
- 产品应用
- ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 31kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human MBLAC2
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
MBLAC2 is a 279 amino acid protein that belongs to the glyoxalase II family and metallo-β-lactamase superfamily. Existing as two alternatively spliced isoforms, MBLAC2 binds two zinc ions and is encoded by a gene that maps to human chromosome 5q14.3. Chromosome 5 contains 181 million base pairs and comprises nearly 6% of the human genome. Chromosome 5 is associated with Cockayne syndrome through the ERCC8 gene and familial adenomatous polyposis through the adenomatous polyposis coli (APC) tumor suppressor gene. Treacher Collins syndrome is also chromosome 5-associated and is caused by insertions or deletions within the TCOF1 gene. Deletion of the p arm of chromosome 5 leads to Cri du chat syndrome, while deletion of the q arm or of chromosome 5 altogether is common in therapy-related acute myelogenous leukemias and myelodysplastic syndrome.
Similarity:
Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.
Database links:Entrez Gene: 153364Human
SwissProt: Q68D91Human
Unigene: 64004Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.