产品中心
当前位置：首页>产品中心Anti-MAP4K3/GLK/AF555
货号： bs-18666R-AF555 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-18666R-AF555
- 英文名称
- Anti-MAP4K3/GLK/AF555
- 中文名称
- AF555标记的生发中心激酶样激酶抗体
- 别 名
- Germinal center kinase like kinase; Germinal center kinase-related protein kinase; GLK; MAPK/ERK kinase kinase kinase 3; MAPKKKK3; MEK kinase kinase 3; MEKKK 3; MEKKK3; mitogen-activated protein kinase kinase kinase kinase 3; RAB8IPL1.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 细胞生物 信号转导 激酶和磷酸酶
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep,
- 产品应用
- ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 101kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human MAP4K3/GLK
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
This gene encodes a member of the mitogen-activated protein kinase kinase kinase kinase family. The encoded protein activates key effectors in cell signalling, among them c-Jun. Alternatively spliced transcripts encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jul 2012]
Function:
May play a role in the response to environmental stress. Appears to act upstream of the JUN N-terminal pathway.
Subunit:
Interacts with SH3GL2. Interaction appears to regulate MAP4K3-mediated JNK activation
Subcellular Location:
Cytoplasmic and Nuclear
Tissue Specificity:
Ubiquitously expressed in all tissues examined, with high levels in heart, brain, placenta, skeletal muscle, kidney and pancreas and lower levels in lung and liver.
Similarity:
Belongs to the protein kinase superfamily.
STE Ser/Thr protein kinase family. STE20 subfamily.
Contains 1 CNH domain.
Contains 1 protein kinase domain.
Database links:Entrez Gene: 8491Human
Entrez Gene: 225028Mouse
Entrez Gene: 170920Rat
Omim: 604921Human
SwissProt: Q8IVH8Human
SwissProt: Q99JP0Mouse
SwissProt: Q924I2Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.