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货号： bs-18652R-AF555 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-18652R-AF555
- 英文名称
- Anti-MANEA/AF555
- 中文名称
- AF555标记的甘露糖苷酶2抗体
- 别 名
- 2-mannosidase; 4932703L02; Alpha 1,2 endomannosidase; DKFZp686D20120; Endo alpha D mannosidase; ENDO; Endo-alpha mannosidase; Endomannosidase; FLJ12838; Glycoprotein endo alpha 1,2 mannosidase; Glycoprotein endo-alpha-1; Glycoprotein endo-alpha-1,2-mannosidase; hEndo; Mandaselin; MANEA; MANEA_HUMAN; Mannosidase endo alpha; OTTMUSP0000000508; RP23-424K9.1.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 细胞生物 免疫学
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Pig, Cow, Horse, Rabbit, Sheep, Cat,
- 产品应用
- ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 54kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human MANEA
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
N-glycosylation of proteins is initiated in the endoplasmic reticulum (ER) by the transfer of the preassembled oligosaccharide glucose-3-mannose-9-N-acetylglucosamine-2 from dolichyl pyrophosphate to acceptor sites on the target protein by an oligosaccharyltransferase complex. This core oligosaccharide is sequentially processed by several ER glycosidases and by an endomannosidase (E.C. 3.2.1.130), such as MANEA, in the Golgi. MANEA catalyzes the release of mono-, di-, and triglucosylmannose oligosaccharides by cleaving the alpha-1,2-mannosidic bond that links them to high-mannose glycans (Hamilton et al., 2005 [PubMed 15677381]).[supplied by OMIM, Sep 2008]
Subcellular Location:
Golgi apparatus membrane.
Tissue Specificity:
Highly expressed in the liver and kidney. Expressed at lower levels in muscle, pancreas, heart, placenta, lung and brain.
Post-translational modifications:
Undergoes proteolytic cleavage in the C-terminal region.
Similarity:
Belongs to the glycosyl hydrolase 99 family.
Database links:Entrez Gene: 79694Human
Entrez Gene: 242362Mouse
Entrez Gene: 140808Rat
Omim: 612327Human
SwissProt: Q5SRI9Human
SwissProt: Q6NXH2Mouse
SwissProt: Q5GF25Rat
Unigene: 533323Human
Unigene: 245602Mouse
Unigene: 10855Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.