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货号： bs-18633R-AF555 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-18633R-AF555
- 英文名称
- Anti-MAGT1/AF555
- 中文名称
- AF555标记的镁转运蛋白1抗体
- 别 名
- bA217H1; DKFZp564K142; FLJ14726; IAG2; IAP; Implantation-associated protein; Magnesium transporter 1; MagT1; MGC64926; MRX95; Oligosaccharyltransferase 3 homolog B; OST3B; OTTHUMP00000023589; OTTHUMP00000062081; PRO0756; RP11-217H1.1.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 细胞生物 结合蛋白
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep,
- 产品应用
- ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 35kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human MAGT1
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
This gene encodes a magnesium cation transporter protein that localizes to the cell membrane. This protein also associates with N-oligosaccharyl transferase and therefore may have a role in N-glycosylation. Mutations in this gene cause mental retardation X-linked type 95 (MRX95). This gene may have multiple in-frame translation initiation sites, one of which would encode a shorter protein with an N-terminus containing a signal peptide at amino acids 1-29. [provided by RefSeq, Jan 2010]
Function:
May be involved in N-glycosylation through its association with N-oligosaccharyl transferase. May be involved in Mg2+ transport in epithelial cells.
Subunit:
Weakly associates with the oligosaccharyl transferase (OST) complex which contains at least RPN1/ribophorin I, RPN2/ribophorin II, OST48, DAD1, and either STT3A or STT3B
Subcellular Location:
Cell membrane.
Tissue Specificity:
Ubiquitous. Expressed at very low levels in brain, lung and kidney.
DISEASE:
Immunodeficiency, X-linked, with magnesium defect, Epstein-Barr virus infection and neoplasia (XMEN) [MIM:300853]: A disease characterized by CD4 lymphopenia, severe chronic viral infections, and defective T-lymphocyte activation.
Note: The disease is caused by mutations affecting the gene represented in this entry.
Similarity:
Belongs to the OST3/OST6 family.
Contains 1 thioredoxin domain.
Database links:Entrez Gene: 84061Human
Entrez Gene: 67075Mouse
Entrez Gene: 116967Rat
Omim: 300715Human
SwissProt: Q9H0U3Human
SwissProt: Q9CQY5Mouse
SwissProt: O35777Rat
Unigene: 323562Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.