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货号： bs-18608R-AF555 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-18608R-AF555
- 英文名称
- Anti-MMGL/Macrophage specific lectin/AF555
- 中文名称
- AF555标记的巨噬细胞特异性凝集素抗体
- 别 名
- carbohydrate-binding protein 35; CBP35; GAL3; galactose-specific lectin 3; GALBP; IgE-binding protein; laminin-binding protein; lectin galactoside-binding soluble 3 (galectin 3); LGALS2; MAC-2 antigen; MAC2; Macrophage asialoglycoprotein binding protein 1; Macrophage galactose specific lectin 1; MASGP BP; Mgl; Mgl1; MMGL.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 细胞生物 免疫学
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- 产品应用
- ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human MMGL/Macrophage specific lectin
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
The antigen is found on the surface of connective tissue macrophages and their precursor cells in bone marrow. Macrophage cell lines (J774-1.6, RAW309Cr.1, WR19M.1) corresponding to mature macrophages express high levels of the antigen.
Function:
Recognizes terminal galactose and N-acetylgalactosamine units. May participate in the interaction between tumoricidal macrophages and tumor cells. Plays a role in the recruitment of inflammatory monocytes to adipose tissue in diet-induced obesity.
Subunit:
Homooligomer. Interacts with SIGLEC1, which may act as a counter-receptor for CLEC10A in lymph node.
Subcellular Location:
Membrane; Single-pass type II membrane protein.
Tissue Specificity:
Detected in lymph node in the subcapsular sinus, interfollicular regions, T and B-cell boundary and in the areas surrounding high endothelial venules (at protein level). Expressed on the surface of activated macrophages. Expressed in heart, lung, testis, skeletal muscle, spleen, brain, kidney and thymus. Expressed in P388, RAW 264.7 and M1 cell lines.
Similarity:
Contains 1 C-type lectin domain.
Database links:Entrez Gene: 17312Mouse
SwissProt: P49300Mouse
Unigene: 252405Mouse
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.