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货号： bs-18557R-AF555 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-18557R-AF555
- 英文名称
- Anti-ZCCHC8/AF555
- 中文名称
- AF555标记的ZCCHC8蛋白抗体
- 别 名
- DKFZp434E2220; ZCCHC8; ZCHC8_HUMAN; Zinc finger CCHC domain containing 8; Zinc finger CCHC domain containing protein 8; Zinc finger CCHC domain-containing protein 8.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 转录调节因子 锌指蛋白 表观遗传学
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep,
- 产品应用
- ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 78kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human ZCCHC8
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- Function:
May be involved in pre-mRNA splicing.
Subunit:
Component of a nuclear TRAMP-like complex, an ATP-dependent exosome regulatory complex consisting of an helicase (SKIV2L2/MTR4), an oligadenylate polymerase (PAPD5 or PAPD7), and a substrate specific RNA-binding factor (ZCCHC7 or ZCCHC8). Several TRAMP-like complexes exist with specific compositions and are associated with nuclear, or nucleolar RNA exosomes. Identified in the spliceosome C complex.
Subcellular Location:
Nucleus
Similarity:
Belongs to the ZCCHC8 family.
Contains 1 CCHC-type zinc finger.
Database links:Entrez Gene: 55596Human
Entrez Gene: 70650Mouse
Entrez Gene: 288661Rat
SwissProt: Q6NZY4Human
SwissProt: Q9CYA6Mouse
Unigene: 37706Human
Unigene: 279427Mouse
Unigene: 144000Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.