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货号： bs-18551R-AF555 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-18551R-AF555
- 英文名称
- Anti-ZCCHC24/C10orf56/AF555
- 中文名称
- AF555标记的10号染色体开放阅读框56抗体
- 别 名
- C10orf56; Chromosome 10 open reading frame 56; Zinc finger CCHC domain-containing protein 24; Zinc finger, CCHC domain containing 24.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 细胞生物 免疫学 锌指蛋白 表观遗传学
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Chicken, Pig, Cow, Horse, Rabbit, Zebrafish, Danio
- 产品应用
- ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 27kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human ZCCHC24/C10orf56
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
ZCCHC24 is a 241 amino acid protein that contains one CCHC-type zinc finger, suggesting a role in transcriptional regulation. The gene encoding ZCCHC24 maps to human chromosome 10, which contains over 800 genes and 135 million nucleotides, making up nearly 4.5% of the human genome. PTEN is an important tumor suppressor gene located on chromosome 10 and, when defective, causes a genetic predisposition to cancer development known as Cowden syndrome. The chromosome 10 encoded gene ERCC6 is important for DNA repair and is linked to Cockayne syndrome which is characterized by extreme photosensitivity and premature aging. Tetrahydrobiopterin deficiency and a number of syndromes involving defective skull and facial bone fusion are also linked to chromosome 10. As with most trisomies, trisomy 10 is rare and is deleterious.
Database links:Entrez Gene: 219654Human
Entrez Gene: 71918Mouse
Entrez Gene: 361104Rat
SwissProt: Q8N2G6Human
SwissProt: B2RVL6Mouse
Unigene: 523080Human
Unigene: 41904Mouse
Unigene: 44060Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.