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货号： bs-18548R-AF555 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-18548R-AF555
- 英文名称
- Anti-Beta-phosphoglucomutase/AF555
- 中文名称
- AF555标记的ß磷酸葡萄糖变位酶/ß-phosphoglucomutase抗体
- 别 名
- Beta PGM;pgmB; Beta-phosphoglucomutase; Glucose phosphomutase 1; Glucose phosphomutase; PGM.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 细胞生物 信号转导 通道蛋白 新陈代谢
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Lactococcus lactis
- 产品应用
- ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 24kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from Lactococcus la
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
Beta-phosphoglucomutase is an enzyme that transfers a phosphoryl group on a glucose monomer from the 1 to the 6 position in the forward direction or the 6 to the 1 position in the reverse. Specifically, it converts Beta-D-glucose-1-phosphate to Beta-D-glucose-6-phosphate. This enzyme participates in both the breakdown and synthesis of glucose. Maltose metabolism in Lactococcus lactis involves the conversion of beta-glucose 1-phosphate to glucose 6-phosphate, a reaction which is reversibly catalysed by a maltose-inducible and glucose-repressible beta-phosphoglucomutase (beta-PGM). Alpha-PGM is expressed constitutively. Beta-phosphoglucomutase is a member of the haloacid dehalogenase superfamily of hydrolase enzymes. The enzyme from Lactococcus lactis has been extensively characterised including a remarkable crystal structure which traps the pentacoordinate transition state.
Function:
Catalyzes the interconversion of D-glucose 1-phosphate (G1P) and D-glucose 6-phosphate (G6P), forming beta-D-glucose 1,6-(bis)phosphate (beta-G16P) as an intermediate. The beta-phosphoglucomutase (Beta-PGM) acts on the beta-C1 anomer of G1P. Glucose or lactose are used in preference to maltose, which is only utilized after glucose or lactose has been exhausted. It plays a key role in the regulation of the flow of carbohydrate intermediates in glycolysis and the formation of the sugar nucleotide UDP-glucose.
Subcellular Location:
Cytoplasmic
Post-translational modifications:
Autophosphorylated.
Similarity:
Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family.
Database links:
Entrez Gene: 1114041 Lactococcus lacti
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.