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货号： bs-18499R-AF555 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-18499R-AF555
- 英文名称
- Anti-ZNF711/ZNF5/AF555
- 中文名称
- AF555标记的锌指蛋白711抗体
- 别 名
- CMPX1; dJ75N13.1; MRX97; Zfp711; Zinc finger protein 6 (CMPX1); Zinc finger protein 6; Zinc finger protein 711; ZN711; ZN711_HUMAN; ZNF4; ZNF5; ZNF6; ZNF711.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 发育生物学 神经生物学 转录调节因子 锌指蛋白 表观遗传学
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Dog, Cow, Horse, Rabbit, Sheep,
- 产品应用
- ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 87kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human ZNF711/Z
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
This gene encodes a zinc finger protein of unknown function. It bears similarity to a zinc finger protein which acts as a transcriptional activator. This gene lies in a region of the X chromosome which has been associated with mental retardation. [provided by RefSeq, Jul 2008]
Function:
Transcription regulator required for brain development. Probably acts as a transcription factor that binds to the promoter of target genes and recruits PHF8 histone demethylase, leading to activate expression of genes involved in neuron development, such as KDM5C.
Subcellular Location:
Nucleus.
Tissue Specificity:
Expressed in neural tissues.
Post-translational modifications:
Phosphorylated upon DNA damage, probably by ATM or ATR.
DISEASE:
Defects in ZNF711 are the cause of mental retardation X-linked ZNF711-related (MRXZ) [MIM:300803]. Mental retardation is characterized by significantly below average general intellectual functioning associated with impairments in adaptative behavior and manifested during the developmental period.
Similarity:
Belongs to the krueppel C2H2-type zinc-finger protein family.
Contains 12 C2H2-type zinc fingers.
Database links:Entrez Gene: 526026Cow
Entrez Gene: 7552Human
Entrez Gene: 245595Mouse
Entrez Gene: 302327Rat
Omim: 314990Human
SwissProt: Q9Y462Human
SwissProt: A2ANX9Mouse
Unigene: 326801Human
Unigene: 259846Mouse
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.