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货号： bs-18488R-AF555 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-18488R-AF555
- 英文名称
- Anti-ZNF639/AF555
- 中文名称
- AF555标记的锌指蛋白639抗体
- 别 名
- ZNF 639;6230400O18Rik; ANC 2H01; ANC_2H01; MGC157200; OTTHUMP00000212173; OTTHUMP00000212174; OTTHUMP00000212175; OTTHUMP00000212195; OTTHUMP00000212197; ZASC1; Zfp639; Zinc finger amplified in esophageal squamous cell carcinomas 1; Zinc finger protein 639; Zinc finger protein ANC 2H01; Zinc finger protein ANC_2H01; Zinc finger protein ZASC1; ZN639_HUMAN; ZNF 639; Znf639; ZNF639 zinc finger protein 639.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 细胞生物 转录调节因子 表观遗传学
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit,
- 产品应用
- ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 56kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human ZNF639
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
ZNF639 is a 485 amino acid protein that localizes to the nucleus and contains five C2H2-type zinc fingers. One of several members of the Krueppel C2H2-type zinc-finger family, ZASC1 is thought to be involved in transcriptional regulation. The gene encoding ZASC1 maps to human chromosome 3, which houses over 1,100 genes, including a chemokine receptor (CKR) gene cluster and a variety of human cancer-related gene loci. Key tumor suppressing genes on chromosome 3 include those that encode the apoptosis mediator RASSF1, the cell migration regulator HYAL1 and the angiogenesis suppressor SEMA3B. Marfan Syndrome, porphyria, von Hippel-Lindau syndrome, osteogenesis imperfecta and Charcot-Marie-Tooth Disease are a few of the numerous genetic diseases associated with chromosome 3.
Function:
Binds DNA and may function as a transcriptional repressor.
Subunit:
Interacts with CTNNA2.
Subcellular Location:
Nucleus.
Similarity:
Belongs to the krueppel C2H2-type zinc-finger protein family.
Contains 8 C2H2-type zinc fingers.
Database links:Entrez Gene: 51193Human
Entrez Gene: 523536Cow
Entrez Gene: 67778Mouse
Entrez Gene: 683504Rat
SwissProt: A5PK30Cow
SwissProt: Q9UID6Human
SwissProt: Q99KZ6Mouse
SwissProt: Q5PPG4Rat
Unigene: 632578Human
Unigene: 285620Mouse
Unigene: 116062Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.