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货号： bs-18477R-AF555 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-18477R-AF555
- 英文名称
- Anti-BLCAP/AF555
- 中文名称
- AF555标记的膀胱癌相关蛋白BLCAP抗体
- 别 名
- Bc10; Bladder cancer 10 kDa protein; Bladder cancer related protein (10kD); Bladder cancer-associated protein; BLCAP; BLCAP_HUMAN.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 肿瘤 细胞生物 免疫学 细胞凋亡
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Pig, Cow, Horse, Rabbit, Sheep,
- 产品应用
- ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 10kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human BLCAP
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
This gene encodes a tumor suppressor protein that reduces cell growth by stimulating apoptosis. The first intron of this gene contains the neuronatin gene, which is imprinted and only expressed from the paternal allele. This gene is imprinted in brain where it is differentially expressed from different promoters. Transcription from the upstream promoter occurs preferentially on the maternal allele, and transcripts are preferentially expressed from the downstream promoter on the paternal allele. Alternative promoters and alternative splicing result in multiple transcript variants that encode the same protein.[provided by RefSeq, Nov 2009]
Function:
May regulate cell proliferation and coordinate apoptosis and cell cycle progression via a novel mechanism independent of both p53/TP53 and NF-kappa-B.
Subcellular Location:
Membrane.
Tissue Specificity:
Expressed in cervical tissues. Down-regulated during bladder cancer progression and in most cervical carcinomas.
Similarity:
Belongs to the BLCAP family.
Database links:Entrez Gene: 10904Human
Entrez Gene: 53619Mouse
Entrez Gene: 171113Rat
Omim: 613110Human
SwissProt: P62952Human
SwissProt: P62951Mouse
SwissProt: P62950Rat
Unigene: 472651Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.